En kannusta ketään tupakoimaan, vaan mielestäni smoking sucks, mutta joitain outoja tuloksia löytyy testosteronin suhteen. En tiedä onko tätä asiaa käsitelty täällä:
Esim:
J Clin Endocrinol Metab. 2005 Feb;90(2):712-9. Epub 2004 Nov 9:
http://www.ncbi.nlm.nih.gov/entrez/...d&dopt=Abstract&list_uids=15536158&query_hl=6
"Smoking seemed to decrease the risk of hypogonadism, but the association was not significant. Decreased cigarette smoking during follow-up increased the risk of hypogonadism, at least as defined by total testosterone levels, and was also associated with larger decreases in testosterone during follow-up.
Most cross-sectional studies have shown a positive association of smoking with total or free testosterone levels (22, 23, 24, 25, 26), present already at 12–14 yr of age (26). Of the sparse prospective data available, baseline smoking predicted larger declines in testosterone during a 13-yr follow-up of the Multiple Risk Factor Intervention Trial study (44). On the other hand, smoking cessation decreased testosterone levels in 1104 men followed for idiopathic infertility (24).
The mechanisms by which cigarette smoking may increase testosterone levels are unclear, but nicotine-mediated inhibition of aromatase (45) has been suggested to explain low estrogen and high androgen levels in women smokers (46). Consistent with this hypothesis, the aromatase inhibitor anastrozole has been shown to increase total and bioavailable testosterone levels in elderly men with low testosterone levels (47). The decrease in testosterone and increase in hypogonadism as a result of decreased smoking could also be secondary to weight gain and increased abdominal obesity, but adjustment for waist girth and its changes did not attenuate the relationship. Weight control through diet and exercise should nonetheless be actively encouraged for men who quit smoking, as increased abdominal obesity and its accompanying negative health consequences may partially offset the substantial health gains of smoking cessation."
Lähteitä
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