No mikä tossa nyt ei vielä mennyt perille. Etsi se todiste nyt tai ole hiljaa, jaksa tota lässytystä enää.
Lähde:
https://www.mja.com.au/public/issues/aug19/corrigan/corrigan.html
"Other psychiatric changes
Several psychiatric disorders have been reported in association with anabolic steroid use since the first case was described in 1980. 38,39 The full list includes schizophrenia, 38 hypomania and mania, 40 delirium, 41 depression, 42 suicide, 10,28,43 and paranoia. 44
In the first reported case of anabolic steroid-related psychiatric disorder, in 1980, a 17-year-old male body builder developed acute schizophrenia when taking methandienone; he recovered on stopping the drug, but relapsed when he took it again. 38 In 1992, Freinhar and Alvarez 40 noted that referring doctors "often" commented on mood changes accompanying anabolic steroid therapy, and described a 27-year-old body builder with hypomania who was taking oxandrolone. He recovered on withdrawal of the drug but had a second attack when taking oxymetholone. A toxic confusional state with choreiform movements occurred in another patient taking 200-300 mg a day of oxymetholone; the condition improved on drug withdrawal. 41
Perry et al. studied 20 weight lifters taking anabolic steroids and 20 controls using a self-administered questionnaire and an interview. 45 The questionnaire showed an increase in psychotic features in the users, including paranoid thoughts, depression, increased hostility and aggression.
Pope and Katz in 1987 reported two cases of psychosis in anabolic steroid users, 46 and then, in 1988, 41 cases (39 men) with a wide range of psychiatric problems. 47 This study was widely criticised because it was not a controlled, prospective trial and because of its selection of subjects. In 1994, they rectified this with a controlled study of 88 athletes who used anabolic steroids and 68 controls. 48 The Structured Clinical Interview for DSM-III-R was used for diagnosis; 25% showed evidence of drug dependence and 23% hypomania, mania or depression. Aggression or violence "often" accompanied hypomanic or manic episodes. The authors also suggested that steroid users are most vulnerable to major depressive episodes during the first three months after discontinuing anabolic steroid use.
Depression has been mentioned previously in relation to drug withdrawal and dependence. Testosterone was formerly used to treat depression, but it is now known to cause it. 49 Suicide may also be a problem with either anabolic steroid drug dependence or after drug withdrawal (especially with sudden withdrawal). It is not often reported in medical journals, but may be reported in the press. Brower et al. reported a body builder who had suicidal thoughts of crashing his car, and warned of the dangers of anabolic steroids and suicide. 32
A different view of anabolic steroid complications was taken by Dimeft and Malone: 50 in 31 current users, 45 previous users and 88 non-users, they found psychiatric diagnoses to be more common in previous users, suggesting that psychiatric disorder may either predispose a person to, or result from, anabolic steroid use.
There is one study which gives a contrary view. Bahrke et al., 51 using two valid psychometric inventories, studied 50 men (12 current steroid users, 14 previous users, and 24 non-users) and concluded that users taking an average daily dose of 45 mg showed minimal psychiatric effects.
In conclusion, this brief review highlights some of the psychological problems encountered with anabolic steroid use. It does not appear that these problems are very common, but future research will show how much disability they cause. "
Oisko se sun vuoro sitten olla hiljaa??
