Ivermektiinistä on ristiriitasta tietoa. Auttaa ja ei auta riippuen tutkimuksesta. Toivottavasti on hyötyä.
''Hauska'' fakta. Intiassa maksaa 2c, jenkeis tonnin.
www.ncbi.nlm.nih.gov
In summary, we believe ivermectin, alone or in combination with other drugs should be seriously considered as a therapeutic intervention in COVID-19.
Time to hospital discharge or clinical recovery was significantly shorter in the largest trials using the highest doses (decreasing from 15-17 days to 5-6 days). Moreover, a higher percentage of patients’ were achieving clinical recovery in the ivermectin-treated groups. The meta-analysis showed a 43% (95% CI 21-67%) higher rate of clinical recovery.
The meta-analysis for survival showed an 83% (95% CI 65-92%) reduction in the risk of death for those taking ivermectin compared with controls.
Doses varied widely and the strongest treatment effects were seen with five days treatment using a 0.4mg/kg dose.
The results described by Dr Hill are based on a meta-analysis of 11 randomised trials. A further 45 trials including 7100 participants) are in progress making a total of 56 randomised trials of ivermectin in 21 countries. In the first quarter of 2021 results are expected for a 500-patient trial in Brazil, a 450-patient trial in Colombia and another large study in Argentina. These numbers will bring the total in completed RCTs up to about 3000 (in line with the numbers used to support approval of remdesivir).
The researchers say that they now need to include the next three randomised trials to confirm the clinical benefits observed in 11 RCTs so far and to agree on the optimal dosage regimen. This work was undertaken at the University of Liverpool with funding from Unitaid, as part of the WHO ACT accelerator programme to improve access to treatments for covid-19.
Vieläkää ei näyttöö tarpeeks? 56 rct:tä tehty. Ei hevillä pääse potilas käyttöön. ''ei niitä tutkita''.