Luin T-nationilta vähän aikaa sitten juttua tuosta CLA:sta. Kerrottiin, että niitä alkuperäisiä tutkimuksia on tulkittu väärin. CLA ei tuon mukaan vähentäisikään rasvan määrää, vaan paremminkin estäisi uuden muodostumista. Eli toisinsanoen dietillä ehkä turha, mutta bulkilla voisi olla hyötyä:
http://www.t-nation.com/readArticle.do?id=461085
"Regarding body fat, the opposite appears true: only the 10,12 isomer affects fat metabolism.(1) Since the human body can’t synthesize trans-10, cis-12 CLA, its intake from dietary sources (e.g. beef, dairy) appears especially important.(1) He then went on to show that 10,12
CLA has NEVER been shown to have lipolytic (fat burning) effects.
Huh? No fat loss, even in rodents? I thought rodent data on lipolysis was repeatedly referenced in sales materials! I listened closer. "You see, t-10, c-12 CLA primarily prevents lipogenesis (adipocyte filling), which is why the constantly growing rats don’t become as fat as their placebo-fed counterparts." That is, rat-fat cells don’t seem to enlarge in the presence of 10, 12 CLA. This is news because rats normally grow larger and fatter throughout their lifespan. The 10,12 isomer prevents this.
One mechanism involved in this was the inhibition of lipoprotein lipase (LPL), the enzyme responsible for dragging fat out of the blood and into fat cells.(1) Another was the inhibition of delta-9 desaturase, a key enzyme in lipogenesis.(1) Ahh; it was coming together now. The advertising propagandists had missed the point.
Reduction of existing fatty tissue was not the effect, prevention of body fat accumulation was!
My bodybuilder’s mind started to take over. The REAL application here is not to try getting ripped with CLA but rather to use it during a "bulking phase," when voracious eating would otherwise pack on some fat — just like with those little rats. I had my own data(2,3) suggesting that a 7.2 g per day dose might improve feed efficiency (more tissue gain at a given amount of food) without fat gain in college weight trainers, so I was feeling vindicated at this point. "