- Liittynyt
- 17.8.2006
- Viestejä
- 16 308
''Keto for glucose tolerance and lipid profile in young women: not so good
The main aim of this study was to investigate the effect of three-week energy-balanced LCHF-diet, with >75 percentage energy (E%) from fat, on glucose tolerance and lipid profile in normal weight, young, healthy women.
The second aim of the study was to investigate if a bout of exercise would prevent any negative effect of LCHF-diet on glucose tolerance.
An LCHF diet with 78 E% fat decreased fasting glucose levels significantly. The diet did not affect fasting insulin or AUC insulin. Free fatty acids, total cholesterol, LDL and LDL/HDL ratio increased significantly.
The LCHF diet, followed by two relative large glucose loads on consecutive days has likely caused a metabolic inflexibility, where a bout of exercise was not adequate to counteract the adaptation to the diet.
The positive effect of exercise on glucose tolerance seen prior to the intervention was blunted after the intervention.
Our data suggest that LCHF diets should not be recommended to healthy, normal weight females, considering the negative changes observed in LDL and total cholesterol, that isolated are factors linked to increased risk for CVD.''
www.frontiersin.org
The main aim of this study was to investigate the effect of three-week energy-balanced LCHF-diet, with >75 percentage energy (E%) from fat, on glucose tolerance and lipid profile in normal weight, young, healthy women.
The second aim of the study was to investigate if a bout of exercise would prevent any negative effect of LCHF-diet on glucose tolerance.
An LCHF diet with 78 E% fat decreased fasting glucose levels significantly. The diet did not affect fasting insulin or AUC insulin. Free fatty acids, total cholesterol, LDL and LDL/HDL ratio increased significantly.
The LCHF diet, followed by two relative large glucose loads on consecutive days has likely caused a metabolic inflexibility, where a bout of exercise was not adequate to counteract the adaptation to the diet.
The positive effect of exercise on glucose tolerance seen prior to the intervention was blunted after the intervention.
Our data suggest that LCHF diets should not be recommended to healthy, normal weight females, considering the negative changes observed in LDL and total cholesterol, that isolated are factors linked to increased risk for CVD.''
Frontiers | Effect of a Low-Carbohydrate High-Fat Diet and a Single Bout of Exercise on Glucose Tolerance, Lipid Profile and Endothelial Function in Normal Weight Young Healthy Females
Low-carbohydrate-high-fat (LCHF) diets are efficient for weight loss, and are also used by healthy people to maintain bodyweight. The main aim of this study ...
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